The fibrous tissue that the body creates to replace damaged skin is called a scar. Scars are also know as cicatrices and are formed as a biological response for repairing skin and other tissue damage in the human body. Although they are most often not considered pretty to look at, a scar is a natural part of the body's healing process. Every wound will result in some form of scarring depending on its severity. The human body's healing process tries hard to repair the skin but it does not get it completely right so to say. The scar tissue intended to replace the skin will most of the time be of less functional quality then the original skin. There are a few examples of tissues that heal without any structural defects or deterioration of function such as a bone break. A break in a bone that is healed will often be more structurally sound then before the break.
Internal Scar Tissue
With vast improvements in technology, modern surgery has helped to save many a life from serious problems ranging from gallstones to appendicitis. These serious illnesses were at one point considered very dangerous, but with modern technology they are no longer classified as being that dangerous. Even though you may think that after your surgery everything is fine, most often it is not. This is due to the fact that surgery induces the body's natural healing abilities creating internal scar tissue where the muscles and tissue have been cut or torn. It is important to note that internal scar tissue is different then "normal" scar tissue. internal scar tissue will often create tethers, barriers and adhesions to internal body structures pulling them out of place and often causing pain.
Anti Fibrosis (Scar Tissue Removal)
Enzymes eat scar tissue and fibrosis. Fibrosis is scar tissue and most doctors learn in anatomy that it is fibrosis that eventually kills us all. As we age, which starts at 27, we have a diminishing of the body's output of enzymes. This is because we make a finite amount of enzymes in a lifetime and we use up a good deal of them by the time we reach our 40's Cystic Fibrosis patients who have virtually no enzyme production to speak of, even as children usually don't make it past their 20's before they die of the restriction and shrinkage in the lungs from the formation of fibrosis or scar tissue.
So our body begins to dole out our enzymes with an eyedropper instead of with a tablespoon. Result: the repair mechanism of the body goes off balance and has nothing to reduce the over abundance of fibrin it deposits in nearly everything from simple cuts, to the inside of our internal organs and blood vessels. It is then when most women begin to develop things like fibrocystic breast disease, uterine fibroids, adhesions, and endometriosis. We all grow arterial sclerotic (meaning scar tissue) plaque, and have fibrin begin to spider web its way inside of our internal organs, reducing their size and function over time. This is why as we age our wounds heal with thicker, less pliable, weaker and very visible scars.
If we replace the lost enzymes, we can control and reduce the amount of scar tissue and fibrosis our bodies have. As physicians in the US are now discovering, even old scar tissue can be "eaten away" from surgical wounds, pulmonary fibrosis, and kidney fibrosis even keloid years after their formation. Medical doctors in Europe and Asia have known this and used orally administered enzymes for such for over 40 years!
Reduce scar tissue buildup, fibrosis, adhesions, arthritic conditions, pain, swelling, inflammation and hundreds of other ailments. Serracor's formulation is more complete and essential than a daily vitamin. Replace the enzymes that Mother Nature has taken away from us as we age. Serracor-NK is radically more advanced than today's leading systemic enzyme blends. Serracor-NK contains several sources of anti-oxidant fighting ingredients, as well as the full spectrum of proteolytic (protein digesting) enzymes, enterically coated to adapt to a wide spectrum of PH levels. Serracor's exclusive formulation contains several highly concentrated digestive enzymes that enable the body to digest fats, proteins, sugars, and carbohydrates. These digestive enzymes convert the food we eat into energy rather than stored fat.
Fibrin is an insoluble protein the body produces in response to bleeding or inflammation. Fibrin performs important functions in the body, including clotting and wound healing. During the blood clotting process, the protein precursor fibrinogen is converted into fibrin, which forms a layer of connective tissue inside the damaged blood vessel. To do this, the fibrin strands assemble into a net-like structure over the damaged vessel and harden, forming a "patch" or small clot to prevent further damage.
Despite its protective function, excessive fibrin can do more harm than good. A high level of circulating fibrin has the potential to accelerate scarring, increase clot formation and impede normal blood flow. This can lead to increased blood viscosity, swelling, edema, pain, chronic inflammation and more serious fibrotic conditions or cardiovascular events.
According to Scripps Research Institute, "It is generally assumed that the persistence of fibrin in the extra cellular matrix (connective tissue) promotes fibrosis, and that the extent of fibrosis is limited by proteases (protein-digesting enzymes) that remove the fibrin. Fibrotic disease occurs when normal control of this process is compromised and excess fibrous material accumulates in the tissues."
The proteases in Serracor-NK® support normal fibrin levels, blood viscosity, overall blood circulation and healthy inflammation responses.*
Serracor-NK for Circulatory & Inflammation Support
Serracor-NK contains SEBkinase® with enteric coated serrapeptase and nattokinase. SEBkinase brings together two enteric coated, fibrinolytic proteases: Peptizyme-SP® (Serrapeptase) and NattoSEB® (our Nattokinase is Vitamin K-free, since it assists in blood coagulation). Serracor NK further supports the activity of SEBkinase-CV with a complete array of proteolytic enzymes, amylase, lipase, CoQ10, herbs and minerals. The net result is a comprehensive systemic enzyme blend designed to support maximum circulatory health.*
Serracor-NK also promotes healthy levels of C-reactive protein (CRP), an inflammation marker and serious risk factor for inflammation and cardiovascular disease.* In addition, the entire systemic enzyme blend is manufactured in a ISO 9001:2000 and GMP certified facilities using our Bioactive Protein Peptide System® (BPPS).
Enteric coated Serrapeptase and Nattokinase: Why is it important?
Most nattokinase and serrapeptase brands on the market are not enteric coated, which means they can lose a significant portion of their fibrinolytic activity and effectiveness in the acidic environment of the stomach. The enteric coating of our Serracor-NK SEBkinase blend allows these sensitive enzymes to survive the acidic conditions of the stomach, thus allowing them to pass into the circulatory system maintaining high activity levels.*
The pH resistant enteric coating will disintegrate after it enters the alkaline environment of the intestines. If your enzyme formula is not enteric coated, you may be wasting your money.
How do Fibrinolytic Units (FU's) relate to enteric coating?
Enzyme activity measured in fibrinolytic units does not mean anything if the enzymes are destroyed and/or denatured in the high acidic conditions of the stomach. Under these conditions, our laboratory tests have consistently shown that serrapeptase and nattokinase lose significant activity when exposed to low pH (such as those in the stomach). In contrast, our enteric coated nattokinase and serrapeptase (the original SEBkinase formula) perform at greater activity levels in the same low pH conditions.
Enzyme Stabilization with BPPS®
The Bioactive Protein Peptides System (BPPS) is a system of peptides used to stabilize and enhance the activity of enzymes.
The Bioactive Protein Peptides System was developed by Specialty Enzymes and Biotechnologies (SEB) specifically for enzyme stability. Stabilizers have been used since SEB began manufacturing enzymes in 1957. The BPPS system was a significant advancement developed by SEB in the early 1990's.
It is true it was not trademarked until 2008, but it was in use long before. The reality is: a pure enzyme is not stable. It requires the addition of stabilizers in order to provide a reasonable shelf life. Because we are the actual manufacturer of enzymes with more than 50 years of manufacturing experience, our research and development team constantly works to improve stability and tolerance to the environments in which the enzymes interact. Marketing companies, on the other hand, will generally have significantly less understanding of the physio-chemical and kinetic properties of enzymes.
Serracor-NK Dosage
For best results, begin enzyme regiment at a low dosage of 1 capsule three times a day. After three days, increase your Serracor-NK dosage to 2 capsules three times a day. After the first week, doses should be adjusted to a therapeutic level of 3 or more capsules three times a day (amount is dependent upon desired benefit).
NOTE: It is important to continue therapeutic doses until results are realized. This should then be reduced to a maintenance dose of 1-3 capsules three times a day.
Complementing your Serracor-NK with additional serrapeptase can increase fibrinolytic activity, as well as increase positive effects on blood pressure and inflammation, and reduce mucus viscosity in the respiratory system.*Serra Rx80 contains 80,000 units of professional-strength serrapeptase per capsule.
Research
Nattokinase Research: Fibrinoyltic Activity
In vitro and in vivo studies have consistently demonstrated the potent fibrinolytic effect of Nattokinase.1 A review of the research on nattokinase demonstrates it may help avoid or reduce the likelihood of deep vein thrombosis, cardiac infarction, pulmonary emboli and stroke. It appears to accomplish this via its fibrinolytic, anti-inflammatory and modulating effect on blood pressure. Studies on hypertension demonstrate an average drop of 10.9% in systolic blood pressure and a 9.7 percent drop in diastolic blood pressure.2,3,4
A study conducted with natto on 12 healthy adults (6 men and 6 women, between the ages of 21 and 55) sought to demonstrate fibrinolytic activity. The volunteers were given 200 grams of natto (the food) before breakfast, and their fibrinolytic activity was tested over time. The results indicate natto generates an increased ability to dissolve blood clots. As a control, researchers later fed the same amount of boiled soybeans to the same volunteers and tracked their fibrinolytic activity. The tests showed no significant change.5
The accumulation of fibrin in blood vessels significantly increases the likelihood of thrombosis formation resulting in a cardiovascular event. For thrombolytic therapy, microbial fibrinolytic enzymes are now much more accepted. The physiochemical properties of this enzyme is becoming well characterized and its effectiveness in thrombolysis in vivo has been further identified.6,7
Nattokinase Benefits & Blood Clots
Blood clots (thrombi) form when strands of fibrin accumulate in the circulatory system. These clots can cause blockage of blood flow. If blood flow is blocked, the oxygen supply to that tissue is cut off and it eventually dies. In the heart, this can result in myocardial infarction (heart attack). In the brain, it can result in strokes or mini-strokes. Deep vein thrombosis can result in pulmonary emboli. All these events can be life-threatening. An in vitro study not only demonstrated the powerful fibrinolytic activity of nattokinase, but also showed the significant reduction in the aggregation of red blood cells and overall lowered whole blood viscosity. The net results are vascular conditions that are less likely to produce blood clots. The authors suggest that nattokinase possesses very real potential as a therapeutic agent in cardiovascular health.8
The process of forming a clot is complex and involves several enzymes. However, the body mainly produces one central enzyme for dissolving a clot, plasmin. It happens that the properties of nattokinase are very similar to plasmin. Nattokinase is particularly effective because it enhances the body's natural ability to fight blood clots in several different ways. It dissolves fibrin directly and appears to enhance the body's natural production of both plasmin and other clot-dissolving enzymes like urokinase. An in vivo study was undertaken to demonstrate the thrombolytic activity of nattokinase, plasmin and elastase on an induced clot in the common carotid artery of laboratory rats. A review of the results indicates that the thrombolytic activity of nattokinase is stronger than that of plasmin or elastase in vivo in this model.9
A fascinating study was conducted to measure the effect of nattokinase in the prevention of deep vein thrombosis and superficial vein thrombosis on extended flights of 7-8 hours on high-risk individuals. The nattokinase group had no thromboses. The placebo group had 5 deep vein thromboses and 2 superficial vein thromboses or 7.6% of 94 individuals. After the flight, the degree of edema was increased by 12% in the placebo group and decreased by 15% in the nattokinase group. The authors concluded that nattokinase was effective in reducing thrombotic events and in controlling edema in high-risk subjects on long flights.10
Serrapeptase Benefits and Respiratory Health
When it comes to the respiratory system, we are constantly at risk of developing health problems, anywhere from the common cold to severe lung diseases. While the cause of any given condition may differ, often time symptoms can manifest themselves and be addressed in similar ways. Clinical testing of serrapeptase reviews its potential with many aspects of respiratory health.
Serrapeptase is widely used in clinical practice in Japan. One research trial in Japan investigated the effect of serrapeptase on sputum properties and symptoms in patients with chronic airway diseases. After 4 weeks of serrapeptase treatment, sputum output, viscosity and sputum neutrophil count decreased significantly. In addition, the frequency of coughing and of expectoration also decreased. The researchers concluded serrapeptase may exert a beneficial effect on mucus clearance by reducing neutrophil numbers and altering the viscoelasticity of sputum in patients with chronic airway diseases.11
Another clinical study reviwed the effect of serrapeptase on the elasticity and viscosity of the nasal mucus in adult patients with chronic sinusitis. Serrapeptase was administered orally for 4 weeks. The dynamic viscosity of the mucus at week 4 was significantly lower than that at week 0. The authors conclude that serrapeptase may have some application in patients with chronic sinusitis.12
The efficacy of serrapeptase was evaluated in a multicentre, double-blind, placebo-controlled study of 193 subjects suffering from acute or chronic ear, nose or throat disorders. After 3-4 days' treatment, significant symptom regression was observed in serrapeptase treated patients. Statistical comparison confirmed the greater efficacy of serrapeptase against all the symptoms examined. It was concluded that serrapeptase has anti-edemic and fibrinolytic activity and supports the body's healthy response to inflammation.13
Derived from natto, a traditional Japanese food made from fermented soybeans. Natto has been known for centuries for its positive medicinal properties, particularly for cardiovascular disorders. To make nattô, soybeans are fermented with the beneficial bacteria Bacillus natto (sometimes listed as Bacillus subtilis natto). During fermentation, the Bacilli produce enzymatic proteases, the most important of which is nattokinase. Like other proteases, nattokinase has potent anti-inflammatory activity, as well as several other beneficial properties, including fibrinolytic activity.* A researcher, Hiroyuki Sumi, identified the active enzyme in natto and demonstrated its ability to dissolve vascular blood clots. He called this enzyme "nattokinase," meaning "enzyme in natto."
SERRAPEPTASE (Peptizyme SP)
Derived from a species of bacteria originally found in the intestine of silkworms; the bacteria, Serratia mercesans, produces the enzyme that enables the silkworm to dissolve its silken cocoon and emerge after metamorphosis. Serratia is now grown in cultures to produce serrapeptase by fermentation. Numerous research and clinical studies demonstrate serrapeptase's formidable anti-inflammatory, proteolytic (protein dissolving), mucolytic (mucus dissolving) and fibrinolytic (fibrin dissolving) properties. They also show that scar tissue is greatly reduced and proteins involved in the inflammatory process are effectively digested. Serrapeptase is a protease that has been used in Japan and Europe for over four decades for its anti-inflammatory activity.*
Bromelain
A collective name for the proteolytic (protein-digesting) enzymes found in the pineapple plant (Ananas comosus); known for its digestive as well its anti-inflammatory properties. A good substitute for animal-derived enzymes pepsin and trypsin for both digestive and systemic support due to its activity across a wide pH range*
Papain
Obtained from the latex of the fruit of the Papaya tree (Carica papaya); used for centuries as an effective digestive aid.
Lipase
Catalyzes the break-down of fats into essential fatty acids that are needed for healthy tissues and cells*
Proteases
Hydrolyze (break-down) proteins like meat, casein, gelatin, soy, fish and other plant and animal proteins to smaller chains of polypeptides (small proteins) and amino acids for easier uptake throughout the body.
Rutin
Bioflavonoid; strengthens and tones arteries and veins, and provides antioxidant support against free-radicals and inflammation*
Amla
Also known as Indian gooseberry (Emblica officinalis); it is a natural, efficacious antioxidant and is one of the richest sources of absorbable vitamin C.
COENZYME Q10
An essential enzyme and cofactor in metabolism that is naturally made and stored in the liver, kidneys and heart; a vital part of energy production and overall cell health*
MAGNESIUM
An essential mineral used as a co-factor by over 350 enzymes in the body; critical part of cardiovascular and nerve physiology. Magnesium helps relax arteries and assists in proper nerve impulse function*
Directions: Take 1 to 2 capsules three times a day. In three days, if desired benefit is not achieved, increase to 2 to 3 capsules three times a day. Take capsules 30 to 60 minutes before or 2 hours after a meal with 8 oz. of water. Dosage can be increased or reduced as needed to achieve desired benefits.
Store in cool, dry place with the lid tightly closed. Avoid excessive heat. Keep out of the reach of children. Caution:If you are taking anticoagulants, like warfarin type drugs, do not take this without consulting your physician. If you are pregnant, nursing, taking any medication or under medical supervision, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Not intended for use by persons under the age of 18.
This Product does not contain soy.
Free of pesticides, chemicals, preservatives, animal derivatives, dairy, lactose, yeast, fish or shellfish, peanuts, tree nuts, artificial sweeteners and colors.
All individual enzymes and probiotics are kosher-certified, and suitable for vegetarians and vegans.
Bioactive Protein Peptide System (BPPS®) is a proprietary manufacturing process featuring complementary bioactive peptides, ensuring greater enzyme stability, absorption and bio-availability.
BIOMEDIC LABS, LLC Since 2004 Scientifically Advanced Supplements
*The products and the claims made about specific products on or through this site have not been evaluated by the United States Food and Drug Administration and are not intended to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Please view our full Terms Of Use Agreement for more information and the terms and conditions governing your use of this site.
Free of pesticides, chemicals, preservatives, animal derivatives, dairy, lactose, yeast, fish or shellfish, peanuts, tree nuts, artificial sweeteners and colors. 
