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Boost and Strenghten Body's Defense Against Long COVID

with Research-backed, Affordable, Over the Counter Supplements

200 Patient Study Published in Peer-reviewed Journal--Medicines, Finds Supplements to be Effective in Managing Post-COVID Fatigue
Affordable, OTC Solution for Patients with Long COVID
Clinical Study Show 93.33% of Patients on Supplements Found Significant Improvement
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200 patient study published in peer-reviewed journal–MPDI Journals, finds ImmunoSEB and Biome Ultra to be effective in managing Post-COVID Fatigue

Studies Shows Clinical Improvement for Patients on ImmunoSEB and Biome Ultra with Mild to Moderate COVID-19

NIH List ImmunoSEB & Biome Ultra in Fact Sheet for Dietary Supplements in the time of COVID


lmmunoSEBTM is a powerful blend of proteolytic and antioxidant enzymes proven to support a healthy immune response in both the innate and adaptive immune systems. In vivo and in vitro studies, as well as a clinical trial, have shown ImmunoSEBTM is a powerful immunomodulator.

It contains Peptizyme SP™ (serrapeptase), Bromelain, Amylase, Lysozyme, Peptidase, Glucoamylase, Catalase, Papain, Lactoferrin.

Benefits of ImmunoSEBTM

  • Stimulates immune response.
  • Demonstrates synergistic action with antimicrobial agents.
  • Supports performance of antimicrobial agents by improving absorption and site-directed assistance.
  • Demonstrates antifungal, antibacterial and bacteriostatic activity.
  • Promotes normal response to inflammation.

Biome Ultra is a revolutionary, shelf-stable probiotic blend of three spore-forming Bacilli species and prebiotic fructooligosaccharide (FOS) for a healthy gut microbiome.

It contains a triple strength blend of SEBtilis™ (Bacillus subtilis), SEBiotic™ (Bacillus coagulans), and SEBclausii™ (Bacillus clausii).

Benefits of Biome Ultra

  • Triple strength blend with SEBtilis™ (Bacillus subtilis),
    SEBiotic™ (Bacillus coagulans), and SEBclausii™ (Bacillus
    clausii), gram-positive bacteria that supports healthy
    immune function*
  • SEBclausii™ promotes healthy gut microflora during
    and after antibiotic use*
  • SEBtilis™ promotes intestinal homeostasis & production
    of antimicrobial compounds*
  • Prebiotic FOS Supports the Rapid Growth of Beneficial


The research for ImmunoSEB and Biome Ultra has its roots in Pulmonary Fibrosis NOW!, a non-profit organization dedicated to educating and supporting people diagnosed with a rare, progressive lung disease with no cure.  Like Long COVID, the typical symptoms of pulmonary fibrosis are coughing and shortness of breath.  In her research, Director Dr. Neha Shah found evidence showing systemic enzymes can reduce pain, inflammation, infection, swelling, coughing, shortness of breath and increase the quality of life.  So she launched a series of studies on the effects of ImmunoSEB and Biome Ultra in patients with COVID-19.

In an interview with Fox 26 Houston, Dr. Neha Shah discusses the remarkable results.  Watch the full interview, and read the article here.

Clinial Trial & Case Studies


of patients who took ImmunoSEB and Biome Ultra supplements resolve their fatigue in 14 days

of patients confirmed mild to moderate COVID-19 on ImmunoSEB and Biome Ultra found significant improvement on day 10 with shorted hospitalization and quicker recovery

of patients on ImmunoSEB and Biome Ultra experienced any adverse affects

Post-Covid Fatigue


A Randomized Controlled Trial of the Efficacy of Systemic Enzymes and Probiotics in the Resolution of Post-COVID Fatigue

A clinical trial published in the peer-reviewed journal Medicines assessed the safety and efficacy of ImmunoSEBTM (systemic enzyme complex) and Biome Ultra(a spore-forming probiotic blend) in patients experiencing post-Covid fatigue.

Results show participants orally supplementing with a combination of ImmunoSEBTM and  for 14 days had resolution of fatigue and overall improved quality of life. ImmunoSEBTM and Biome Ultra were well-tolerated, and no adverse events were reported, indicating the safety of the combination.

The Chalder Fatigue scale (CFQ-11) indicated significant improvement in 91% of subjects in the test arm (who received supplemental treatment with enzymes and probiotics) versus only 15% of subjects in the control arm (who received the placebo).



Potential of the Combination of a Systemic Enzyme Complex and Probiotics administration to Combat COVID-19: A Randomized Open Label Prospective Analysis


A new study published in Advances in Clinical Toxicology in February 2021 explored the safety and efficacy of the health supplements ImmunoSEBTM and Biome Ultra (probiotic complex) as supplemental therapy in confirmed mild to moderate COVID-19 patients, finding 93% of patients in the test arm showed clinical improvement on day 10 vs. 60% of patients in the control arm.*

Patients in the test arm had:

  • a shorter duration of hospitalization
  • quicker recovery
  • faster reduction in CRP levels

as compared to the control arm. The efficacy and safety of the experimental regimen was compared with the control arm at various time points from days 1 to 21 .*

Post-Viral Fatique

Case Series

Management of Post COVID-19 Fatigue using Systemic Enzymes and Probiotics- Case Series

The Medical Journal of Clinical Trials & Case Studies published a case series on COVID-19 and the lmmunoSEBTM and Biome Ultra combination in March 2021. The participants were post-COVID-19 patients experiencing fatigue with a total fatigue score of more than 22 on the CFQ-11 at baseline.

Patients were treated with ImmunoSEBTM and Biome Ultra for 14 days. Their fatigue score significantly declined during the course of treatment.

Researchers summarize: “The present cases demonstrate that a 14 days supplementation of lmmunoSEBTM + Biome Ultra significantly reduces post-COVID-19 fatigue in patients. The proposed supplement regimen could be a potential tool to aid in the recovery of COVID-19 patients, many of whom continue to experience severe fatigue several months after initial infection. A large-scale, placebo-controlled prospective study is warranted to further evaluate this effect.”


“ImmunoSEB and Biome Ultra has been a critical part of my post-COVID brain fog recovery. I can truly tell a difference from these supplements and feel like I have “me” back. I am forever grateful to have found these supplements and plan to take them forever!”

– Dr. Emily Splichal | DPM

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