Taking melatonin and chamomile together may enhance sleep by combining melatonin’s role in regulating the sleep-wake cycle with chamomile’s calming effects. Melatonin, a hormone naturally produced in response to darkness, helps signal the body to sleep and can be especially useful for those with disrupted sleep patterns or jet lag. Chamomile, often consumed as tea, contains apigenin, a compound known for its anxiety-reducing and relaxation-promoting properties. Together, they may create a synergistic effect—melatonin helping to time sleep appropriately, while chamomile eases the transition into sleep—potentially leading to faster sleep onset, improved sleep quality, and fewer nighttime awakenings.